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Comprehensive information resources about WES testing

How Does WES Work?

1

DNA Isolation

DNA is extracted and purified from your blood or saliva sample.

2

Exome Capture

Protein-coding regions are targeted with specific probes.

3

Sequencing

High-accuracy sequencing on the Illumina NovaSeq platform.

4

Analysis & Report

Variants are classified and reported according to ACMG guidelines.

WES vs WGS Comparison

✅ WES (Whole Exome)

  • ~20,000 gene coding regions (~1-2% genome)
  • Lower cost
  • Faster analysis and interpretation
  • Covers 85% of known disease variants

WGS (Whole Genome)

  • Entire genome (~3 billion base pairs)
  • Higher cost
  • Longer analysis time
  • Includes non-coding region variants

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