Genetic Counseling After WES Testing: What Do the Results Mean?

The WES test, or Whole Exome Sequencing, has created a significant revolution in the diagnosis of genetic diseases. For families, especially those with suspicions of unexplained neurological, developmental, metabolic, or rare diseases affecting themselves or their children, this test is an important source of hope. However, the results of the WES test may not always provide the expected clarity. Therefore, the genetic counseling process is of great importance. In this article, we will discuss what genetic counseling means after the WES test and what families can do during this process.

Understanding WES Test Results

The results of the WES test provide information related to the detection of genetic changes (variants). However, not every detected genetic change may cause disease. While some variants may not have an impact on health, others may be associated with specific diseases. At this point, genetic counseling services come into play. Genetic counselors share the results with families, explaining which genetic changes require further investigation or which situations are less concerning. They also clearly express what the obtained results mean for family members.

Genetic Counseling Process

Genetic counseling after the WES test typically consists of the following stages:

1. Presentation of Results: The genetic counselor presents the test results to the family in clear and understandable language. Here, the meaning of genetic changes, potential health effects, and the steps to be followed are explained in detail.
1. Risk Assessment: The family is informed about the risk of certain genetic diseases. The risk of transmission of genetic changes among family members is assessed by the genetic counselor.
1. Family Planning: The genetic counselor helps families make informed decisions about future pregnancies. Being aware of which genetic diseases individuals carry after genetic testing plays a critical role in the family planning stage.
1. Follow-Up and Support: After the test results, information is provided about additional supports and follow-up processes that families may need. This can include psychological support, additional tests, or consultations with other specialists.

What to Do After Genetic Testing?

After receiving the WES test results, the steps families should take are as follows:

• Understand the Results: You should review your test results in detail with your genetic counselor. This will help you understand what it means for you and your children.
• Prepare Your Questions: Before your genetic counseling session, write down the questions you have in mind. This will allow you to have a more productive discussion with your counselor.
• Join Support Groups: You can join support groups to learn more about genetic diseases and meet other families with similar experiences.
• Make Informed Decisions for Family Planning: Based on your test results and the recommendations of your genetic counselor, plan your future family planning.

WES Testing and Genetic Counseling with Omega Genetics

As Omega Genetics Laboratory, we perform WES tests in Turkey with the highest accuracy. Thanks to our advanced sequencing infrastructure and international accreditations, we ensure the reliability of your test results. Additionally, we support you and your family throughout this process with our genetic counseling services. For more information and to schedule an appointment, you can visit westesti.com. Your health is our priority!